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What is tramadol? Tramadol is a pain medication that operates in the same way that opioids do. It acts on the central nervous system to ease pain (CNS). Tramadol is a prescription pain reliever that is used to treat moderate to severe pain in adults. Tramadol extended-release is used to manage pain 24 hours a day, seven days a week. This type of tramadol should not be used for pain on an as-needed basis. Warnings Tramadol users have been documented to experience seizures. If you take higher quantities than recommended, you're more likely to have seizures. Seizures are also more likely in people who have a seizure disorder or who are using certain antidepressants or opioids. If you're suicidal or have a history of addiction, you shouldn't use tramadol. Tramadol should not be taken if you have severe respiratory problems, a blockage in your stomach or intestines, or if you have recently used alcohol, sedatives, tranquillizers, narcotic medication, or an MAO inhibitor. Trama...